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Contact the Center
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INVESTIGATORS BY PROJECT FOCUS
Biology Working Groups
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MACROPHAGE WORKING GROUP
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| Name |
Affiliation |
Project focus |
| Alan Aderem |
ISB |
Macrophage secreted proteome |
| Elizabeth Gold |
UW, Cardiology/ISB |
Statins and macrophage activation |
| Peter Gough |
UW, Pathology |
Macrophage shed proteome |
| Katy Kennedy |
ISB |
Macrophage secreted proteome |
| Elaine Raines |
UW, Pathology |
Macrophage shed proteome |
| Lynn Schnapp |
UW, Medicine/Pulmonary |
ARDS alveolar lavage fluid |
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DEVELOPMENT WORKING GROUP
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| Name |
Affiliation |
Project focus |
| Bob Eisenman |
FHCRC, Basic Science |
Myc oncogen function |
| Mark Groudine |
FHCRC, Basic Science |
Beta-globin locus & DNA binding proteins |
| Steve Hauschka |
UW, Biochemistry |
Cardiac-specific enhancer |
| Yuzuru Shiio |
FHCRC, Basic Science |
B Cell chromatin associated proteins |
| Chris Wilson |
UW, Immunology |
Epigenetic regulation in T cell development |
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SIGNALING WORKING GROUP
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| Name |
Affiliation |
Project focus |
| Joe Beavo |
UW, Pharmacology |
Phosphodiesterase in SMC proliferation |
| William Catterall |
UW, Pharmacology |
Calcium channel signaling in cardiac & vascular SMC |
| Hilary Coller |
FHCRC, Basic Science |
Quiescent v. proliferative lung fibroblast |
| John Glomset |
UW, Medicine/Biochemistry |
Membrane associated signaling complexes |
| John Harlan |
UW, Medicine/Hematology |
Endothelial apoptotic signaling complexes |
| Neil Nathanson |
UW, Pharmacology |
Agonist-induced receptor internalization |
| Jim Roberts |
FHCRC, Basic Science |
Quiescent v. proliferative lung fibroblast |
| Steve Schwartz |
UW, Pathology |
Death-associated protein complexes in macrophages |
| Dan Storm |
UW, Pharmacology |
Adenylate cyclase complexes & SMC proliferation |
| Zengui Xia | UW, Pharmacology |
ERK5 protein complexes and cardiac hypertrophy |
Technology Development Working Group
| Name |
Affiliation |
Technology Module |
| Yong Chi |
ISB |
Selective isolation of phosphorylated peptides |
| Hookeun Lee |
ISB |
Separation science |
| Jeff Ranish |
ISB |
Protein complex analysis |
| Yu Lu |
ISB |
Separation science |
| Xiao-Jun Li |
ISB |
Software development |
| Mingliang Ye |
ISB |
Mass spectrometry development |
| Patrick Pedrioli |
ISB |
Protein expression |
| Jimmy Eng |
ISB |
Software development |
| Andrew Keller |
ISB |
Software development |
| Alex Nesvizhskii |
ISB |
Software development |
| Ning Zhang |
ISB |
Software development |
| Benno Schwikowski |
ISB |
Software development |
| Eric Deutsch |
ISB |
Database development |
High Throughput Proteome Facility Staff
| Name/Title |
Field of Study |
Role at SPC |
David R. Goodlett,Ph.D.
Director of Proteomics
Senior Research Scientist |
Chemistry
Biochemistry |
Principle Investigator
Laboratory Manager
Director, Proteomics Facility |
Eugene C. Yi, Ph.D.
Research Scientist |
Chemistry
Biochemistry |
MS Operator
Sample preparation
Method implementation |
Hookeun Lee, Ph.D.
Research Scientist |
Chemistry
Analytical Chemistry |
MS Operator
Sample preparation
Method implementation |
Jimmy Eng, M.S.
Senior Software Engineer |
Electrical Engineering
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Programmer
Collaborator Training |
Wei Yan, Ph.D.
Research Scientist |
Zoology
Biomolecular Chemistry |
MS operator
Data analysis |
Samuel Donohoe
Research Associate II |
Cellular and Molecular Biology |
MS Operator
Sample preparation
Collaborator Training |
Jinzhi (Jenny) Chen, Ph.D.
Postdoctoral Fellow |
Chemistry
Analytical Chemistry |
MS Operator
Sample preparation
Method implementation |
Integrated Systems Biology Working Group
| Name |
Affiliation |
Technology Module |
| Ruedi Aebersold |
ISB |
Quantitative proteomics |
| Anne-Claude Gingras |
ISB |
Systematic perturbation of mammalian cells |
| Alan Aderem |
ISB |
Macrophage biology & single cell assays |
| Elaine Raines |
UW, Pathology |
Macrophage biology/in vivo mouse modeling |
| Tim Galitski |
ISB |
Computational pathway modeling |
| Benno Schwikowski |
ISB |
Computational pathway modeling |
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